A total of three carbazole alkaloids and essential oil from the leaves of Murraya koenigii (Rutaceae) were obtained and examined for their effects on the growth of five antibiotic resistant pathogenic bacteria and three tumor cell lines (MCF-7, P 388 and Hela). The structures of these carbazoles were elucidated based on spectroscopy data and compared with literature data, hence, were.
The traditional use of Murraya koenigii as Asian folk medicine prompted us to investigate its wound healing ability. Three carbazole alkaloids (mahanine (1), mahanimbicine (2), mahanimbine (3)), essential oil and ethanol extract of Murraya koenigii were investigated for their efficacy in healing subcutaneous wounds. Topical application of the three alkaloids, essential oil and crude extract on.
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Murraya koenigii is an edible herb widely used in folk medicine. Here we report that girinimbine, a carbazole alkaloid isolated from this plant, inhibited the growth and induced apoptosis in human hepatocellular carcinoma, HepG2 cells. The MTT and LDH assay results showed that girinimbine decreased cell viability and increased cytotoxicity in a dose-and time-dependent manner selectively.
Molecules, an international, peer-reviewed Open Access journal. Substantial evidence suggests that phenolic extracts of Castanea mollissima spiny burs (CMPE) increase pancreatic cell viability after STZ (streptozotocin) treatment as a result of their antioxidant properties. In the present study, the hypoglycemic and hypolipidemic activities of CMPE were studied in normal and STZ-induced.
Influence of Direction and Type of Applied Force on the Detachment of Macromolecularly-Bound Particles from Surfaces; A General Method for Patterning Gradients of Biomolecules on Surfaces Using Microfluidic Networks.
Curry (Murraya koenigii.) and coriander leaves (Coriandrum sativum) are most consumed leaves in various diets of Indian cuisines and other Asian countries includes Thailand, Malaysia, and Singapore. Both leaves are rich in many bioactive compounds like polyphenols, alkaloids and flavonoids which showed multiple bioactive functions like antioxidant, anticancer, antimicrobial antidiabetic and.
The use of plants in the traditional management of diabetes in Nigeria: Pharmacological and toxicological considerations Udoamaka F. Ezuruike n, Jose M. Prieto 1 Center for Pharmacognosy and Phytotherapy, Department of Pharmaceutical and Biological Chemistry, School of Pharmacy, University of London, 29-39 Brunswick Square, WC1N 1AX London, United Kingdom.
Synthesis, evaluation and molecular modelling studies of 2-(carbazol-3-yl)-2-oxoacetamide analogues as a new class of potential pancreatic lipase inhibitors Author links open overlay panel S.N.C. Sridhar a George Ginson a P.O. Venkataramana Reddy b Mukund P. Tantak b Dalip Kumar b Atish T. Paul a.
India) Design, synthesis and evaluation of lantadene A congener with hydroxyl functionality in ring A as an antitumour agent. Natural Product Research, v. 25(4): p. 387-396, 2011 (Eng; 26 ref).
Journal of Ethnopharmacology.pdf - Free download as PDF File (.pdf), Text File (.txt) or read online for free. Scribd is the world's largest social reading and publishing site. Search Search.
Recent studies and systematic reviews point toward the role of inflammation in the pathogenesis of diabetes and associated complications like CVDs (Ziegler, 2005, Williams and Nadler, 2007, Festa and Steven, 2005, Gleissner et al., 2007, Garcia et al., 2010).Inflammation is a short-term adaptive response of the body to harmful stimuli such as allergens, pathogens, any injury to tissues.
A sulphated polysaccharide from brown algae Sargassum vulgare (SVSP) was extracted and examined with respect to chemical, structural characterization and hypolipidemic effects.
The oxaziridine 3 was previously reported in our earlier research work to be an agent for the transfer of oxygen on organosulfides .The oxaziridine 3 used in the current study was synthesized starting from the commercial tertiary alcohol 1 ().The imine 2 from step (a) was obtained by cyclisation of the tertiary alcohol 1 by a Ritter-type procedure. The peracidic oxidation of imine 2 led to.
In the classic seven-country pro- lism include increased whole body protein turnover, spective study where lipid intake was correlated with CHD increased hepatic protein synthesis, persistent muscle pro-(21,22), the disease incidence was also related to the intake tein breakdown, and decreased levels of plasma branched-of saturated fat. Most dietary prevention trials have re- chain amino acids.
Administration of mahanimbine isolated from the petroleum ether fraction of the leaves decreased blood glucose levels in STZ-induced diabetic rats and had a dose-dependent alpha amylase and alpha glucosidase inhibitory effect (Dineshkumar et. rhamnopyranosyl)benzyl) carbamate. Methyl N-4-( (a-L-rhamnopyranosyl) benzy) carbamate, 0-(2'-hydroxy-3.
Wound Healing and Anti-Inflammatory Effect in Animal Models of Calendula officinalis L. Growing in Brazil.pdf Available via license: CC BY 3.0 Content may be subject to copyright.
The active principle conferring such effect consists of carbazole alkaloids viz. Mahanine, Mahanimbine and Coumarins; the most potent being Mahanimbine. AFLP based Species Specific DNA Marker(s), identified in accessions of Murraya koenigii collected from different altitudinal regions established that all the genotypes used in this study belong to the same species viz. Murraya koenigii.
Protein synthesis acts in this way, that is if there is only the most minuscule mistake it can have monstrous effects. Protein synthesis first begins in a gene. A gene is a section of chromosome compound of deoxyribonucleic acid or DNA.